How do I enable hotkeys in Windows 10?

Method 2: Use the Start Menu
  1. Open the Start Menu.
  2. Navigate to the icon or tile for the app you want. …
  3. Right click and select Open file location. …
  4. Right click on the shortcut icon and select Properties.
  5. Enter a key combination in the “Shortcut key” box.
  6. Click OK.
How do I enable or turn off hotkeys?
Under “Administrative templates” left click on “Windows Components”. Now after you got to “File Explorer” you should have in the right panel a feature that says “Turn Off Windows + X hotkeys”. Double left click or tap the “Turn off Windows + X hotkeys”.